Police officers were called to the Co-op food store in Ruskington on Monday after thieves broke in.
Lincolnshire Police are appealing for witnesses and information following the burglary at the Lincolnshire Co-op on Ruskington High Street.
The break in is said to have happened between 1am and 3am on Monday morning and a large quantity of cigarettes was taken during the burglary.
A police spokesman said: “If anyone has any information that can assist with our investigation, they should call us on 101, referring to incident 27 of November 25.”
The store was temporarily closed as a result of the incident but is said to have re-opened by mid-morning and is trading again.
Staff are working with police to help with their investigation.